George Clooney's new football comedy fumbled at the box office this weekend.

21, the Kate Bosworth casino thriller, retained the No. 1 spot for a second week, raking in $15.1 million.

Leatherheads, co-starring Renée Zellweger and John Krasinski, debuted at No. 2 with $13.5 million.

With mixed reviews, Leatherheads attracted audiences in their 30s and 40s but failed to lure in younger crowds.

"I'm disappointed for us, I'm disappointed for George. I think he's a great guy and think he's got tons of directing talent," Nikki Rocco, head of distribution for Universal, told the Associated Press. "I wish I could have that crystal ball and tell you what went wrong."

Leatherheads almost got beat by Nim's Island, the family adventure starring Jodie Foster and Abigail Breslin, which earned $13.3 million.

The complete top 5:
1. 21, $15.1 million
2. Leatherheads, $13.5 million
3. Nim's Island, $13.3 million
4. Dr. Seuss' Horton Hears a Who, $9.1 million
5. The Ruins, $7.8 million